2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudoUridine

2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudoUridine

2',3'-Bis-O-(t-butyldimethylsilyl)-N1-methylpseudoUridine – a modified nucleoside – is an indispensable constituent for RNA synthesis. Once aligned with RNA strands, RNA polymerases recognize it effortlessly, presenting an excellent model for analyzing RNA secondary structures and protein-RNA bonds. The nucleoside has proven useful, too, in sophisticated RNA medications that precisely target specific malignancies.

Molecular Weight
486.75
Molecular Formula
C22H42N2O6Si2
IUPAC Name
5-((2S,3S,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methylpyrimidine-2,4(1H,3H)-dione
Purity
≥95% by HPLC

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