N1-Methyl-2'-O-MethylpseudoUridine-5'-Triphosphate
A modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA.
Molecular Weight
512.19
Molecular Formula
C11H19N2O15P3
Synonyms
N1,2'-O-Dimethylpseudo-UTP; N1-Methyl-2'-O-Methylpseudo-UTP
IUPAC Name
(((2R,3R,4R,5S)-3-hydroxy-4-methoxy-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-2-yl)methyl)triphosphoric acid
Purity
≥95%
Storage
Storage at -20°C
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Chemical Structure
